Patients with HER-2 positive early breast cancer with residual invasive disease after neoadjuvant therapy were randomly ...

In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine ...

Adjuvant ado-trastuzumab emtansine significantly prolonged survival compared with trastuzumab for certain women with ...

Phase 3 data support pyrotinib plus trastuzumab and docetaxel “as a well-established and effective treatment strategy,” according to Binghe Xu, MD.

Trastuzumab, tested only as a single agent, has been shown to achieve 7% response in heavily pretreated patients with AOC with 3+ and 2+ HER2 immunostaining by immunohistochemistry (IHC).

Trastuzumab pamirtecan is under clinical development by BioNTech and currently in Phase II for Solid Tumor. According to GlobalData, Phase II drugs for Solid Tumor have a 37% phase transition success ...

Share on Facebook. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Subcutaneous administration ...

trastuzumab deruxtecan (T-DXd; Enhertu) or physician's choice of chemotherapy. Patients in the T-DXd group had a median progression-free survival (PFS) of 9.9 months compared with 5.1 months among ...

“We observed that the majority of our trastuzumab resistant cell lines remain sensitive to lapatinib, providing further evidence that these two agents have independent mechanisms of resistance.

From 1 January 2025 Pharmac will fund: osimertinib (branded as Tagrisso) for people with a type of advanced non-small cell lung cancer trastuzumab deruxtecan (branded as Enhertu) for people with ...

Potential practice-changing therapies in gynecologic cancer include the emergence of carboplatin, paclitaxel, and PD-1 ...