The Niners are short-handed when it comes to playmakers on offense with Aiyuk out for the season and All-Pro running back ...

Brandon Aiyuk has been placed on injured reserve, dealing a major blow to the 49ers as they navigate key injuries.

The Dallas Cowboys are set to face off against a team on Sunday that is dealing with just as many injury issues as they have ...

San Francisco 49ers head coach Kyle Shanahan provided a brief update on running back Christian McCaffrey ahead of Wednesday's ...

The San Francisco 49ers may feel compelled to act with wide receiver Brandon Aiyuk lost for the season, worsening their injury crunch. ESPN's Dan ...

San Francisco 49ers RB Christian McCaffrey is currently on pace to return for the second half of the regular season.

Here is a player-by-player look at the 49ers’ injury-ravaged receiving corps entering Sunday’s game against the Dallas ...

Like Dallas, the Niners have struggled through some of the season’s early portion due to various key injuries.

Every fan of the San Francisco 49ers is awaiting for Christian McCaffrey, and now HC Kyle Shanahan has provided a potential ...

The 49ers’ lone screen on Sunday went to rookie Jacob Cowing, who gained nine yards. It’s something he did well in college.

The San Francisco 49ers have fallen well out of the 'Super Bowl contender' range in the USA TODAY NFL power rankings.

San Francisco head coach Kyle Shanahan said running back Christian McCaffrey, who hasn't played all season, could return ...